Shakers are used to continuously agitate or vibrate certain mixtures to effect either homogeneous mixing, wetting, or separation. In this process, holders such as clamps, tension rollers or adhesive mats are used over on platforms (trays) to secure the vessels. Depending on the type of application, 3D tumbling, back-and-forth, circular or overhead movements may be considered. By setting the speed per minute and a deflection (stroke) determined according to the type of device, the shaking motion is transmitted differently to the samples. A special case is the vibration of the mounting platform. The smallest representative of the vibration devices is the vortexer for shaking up small amounts of liquid. For microbiological and cell cultivation applications, incubation shakers with temperature-controlled closed housings are preferred.